Initiation codon for protein synthesis Molecular Biology: Protein Synthesis

Initiation codon for protein synthesis, protein synthesis initiation

Under these types of conditions PERK serves a primary inhibitory function while GCN2 serves a secondary inhibitory role allowing for cell cycle arrest in response to ER stress. The enzymes of the deiodinase family are also important selenocysteine-containing enzymes.

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As the level of heme falls the activity of HRI increases. Indeed, at least 3 distinct mechanisms are known to exist that regulate the level and activity of eIF-4E.

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GTP and elongation factor required. The peptidyl-transferase is an important enzyme which catalyzes the formation of the peptide bonds. There are several signal transduction pathways whose activations lead to phosphorylation of 4E-BPs.

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